Use of coenzyme Q10 in diets for tilapia species and its implication in zootechnical performance: a systematic review with meta-analysis.
antioxidant agent, feed efficiency, daily weight gain, supplementation
Increasing evidence has highlighted Coenzyme Q10 (CoQ10) in improving performance in fish, however, this effect still needs to be systematically analyzed. This systematic review (RS) aims to summarize scientific evidence on the use of CoQ10 in diets for tilapia species and its implications on zootechnical performance. Six databases PubMed, PubMed, Science Direct, Scopus, Web of Science, and Google Scholar were searched using a search strategy for studies that reported the use of CoQ10 in tilapia diets. Relevant literature was examined, and two reviewers extracted information. Methodological quality was assessed using the SYRCLE Risk of Bias Tool instrument. Of the 6 studies eligible for this SR, 4 comprised the meta-analysis (MA) with 1,302 animals that constituted 14 comparisons. Statistical analyses were performed using the Rdata Meta package software. Heterogeneity was observed between studies for all variables, therefore a subgroup analysis was performed. In general, the results showed that the dietary inclusion of CoQ10 at a dose of 20 mg/kg improves performance and health indices and compensates for the harmful impacts of oxidative stress in tilapia, in addition to increasing the resistance of tilapia against different pathogens.