Banca de QUALIFICAÇÃO: LEINAH SILVA SOUZA

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
DISCENTE : LEINAH SILVA SOUZA
DATA : 29/08/2019
HORA: 14:00
LOCAL: IFBA - Sala 12
TÍTULO:

Bioprospecting of bioactive molecule of the Atlantic Forest of the South of Bahia.

PALAVRAS-CHAVES:

Alpha-glycosidase. Acetylcholinesterase. Antioxidant.

PÁGINAS: 71
GRANDE ÁREA: Outra
ÁREA: Ciências Ambientais
RESUMO:

The human being uses plant species for medicinal treatments for a long time and several substances have already been isolated, however, many compounds are still unknown due to the great biodiversity in the plant kingdom. Such compounds derived from plants can have beneficial actions on human health. This potentiality of biomolecules is due to the effects of metabolites, such as the antioxidant action and inhibition of enzymes, such as α-glycosidase and acetylcholinesterase. These enzymes, along with the excessive production of free radicals in the body, are associated with pathological processes such as diabetes, obesity, cardiovascular diseases, neurodegenerative diseases, HIV infections and tumors. Inhibitors of such enzymes have a moderate effect and cause large side effects, necessitating the identification of compounds with more effective action. Thus, the objective of this research is to find bioactive plant species of the Atlantic Forest inhibitor of the enzyme α-glycosidase, acetylcholinesterase and with antioxidant action. Based on this, samples of Clusia nemorosa, Copaifera lucens, Neomarica portosecurensis, Miconia albicans, Croton celtidifolius, Schnella angulosa and Virola gardneri were analyzed for antioxidant activity using the DPPH free radical sequestration method and evaluation of phenolic contents and total flavonoids. The results indicate that all species have antioxidant activity, with different phenolic and flavonoid contents. The research is under way, and therefore such results are partial and further analysis will be carried out.

MEMBROS DA BANCA:
Presidente - 548.407.245-04 - MARCUS LUCIANO SOUZA DE FERREIRA BANDEIRA - IFBA
Externo à Instituição - DANIELA SÉFORA HACKENHAAR - IFBA
Externo à Instituição - MARCUS ANDRADE W JÚNIOR - IFBA