Low back pain is an important health problem in the world, with a high prevalence among workers. It is a complex condition that can be influenced by several biological, psychological, social, cultural and occupational risk factors. Symptoms of pain and physical-functional disability resulting from low back pain directly affect participation at work. Therefore, it is important that interventions to manage low back pain are carried out at all levels of care, including approaches compatible with the occupational context and with the characteristics of the workers. Pain self-management through educational interventions is an approach capable of meeting this need. In this case, workers must have access to knowledge of their own pain experience (self-assessment) and also to content and information related to the neurophysiology of pain and the factors that modulate it (pain education). The use of an application to deliver the pain education program seems to be an innovative, easily accessible solution capable of generating significant learning in the worker so that he can assess and intervene in his health status. Objective: To develop a pain education program to be delivered in digital format (E-Health) through an application for mobile devices for workers with low back pain. Methods: The project will be carried out in 3 stages. Step 1 focuses on the conceptual and structural development of the self-management program; step 2 is aimed at developing the prototype of the mobile application to be used to deliver the program; and, finally, step 3 is intended to assess the acceptability and viability of the prototype. Each step has its own method that follows guidelines and criteria established by international and national recommendations. Preliminary Results: The outcome of step 1 was the development of the conceptual structure of the self-management program through a model that articulates intervention approaches for the prevention and control of low back pain. Each approach has self-assessment tools and specific content selected based on the biopsychosocial model, the path to recovery and the Dutch Multidisciplinary Occupational Health Guideline. In step 2, the prototype of the application for mobile devices was developed with the choice of platform, familiarization with the functionalities, guiding questions, self-assessment instruments and the application's own database. Stage 3 is expected to take place in the second half of 2023.